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Inherent Properties, Identifiers and References
ChemSpider ID: 5293244
Empirical Formula: C6H20N2O12P4153Sm
Molecular Weight: 589.0463
Nominal Mass: 589 Da
Average Mass: 589.0463 Da
Monoisotopic Mass: 588.918762 Da
Quick Links: Permalink Similar Isomers
Systematic Name: [2-(bis(phosphonomethyl)amino)ethyl-(phosphonomethyl)amino]methyl​phosphonic acid; samarium
SMILES:
InChI: InChI=1/C6H20N2O12P4.Sm/c9-21(10,11)3-7(4-22(12,13)14)1-2-8(5-23(​15,16)17)6-24(18,19)20;/h1-6H2,(H2,9,10,11)(H2,12,13,14)(H2,15,16​,17)(H2,18,19,20);/i;1+3
InChIKey: WNYXBFNBLZLWRA-GJNDDOAHEM
(Details...) Wikipedia Article(s)
Samarium-153-ethylene diamine tetramethylene phosphonate, Samarium-153 EDTMP, Quadramet, or simply Samarium-153 is a complex of a radioisotope of the lanthanide element Samarium with carrier EDTMP which is used to treat pain when cancer has spread to the bone. Samarium-153 is injected into a vein and distributes throughout the body. Samarium-153 EDTMP homes in on areas where cancer has invaded the bone. Once there, the radioisotope emits beta particles (electrons) which kill the nearby cancer cells. Pain begins to improve in the first week for most people and the effects can last several months. It is commonly used in lung cancer, prostate cancer, breast cancer, and osteosarcoma. Side effects result from radiation to the bone marrow and include thrombocytopenia and leukopenia. Read more... or Edit at Wikipedia...
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Names and Synonyms

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Lexidrona​m Sm 153

Quadramet [Wiki]

Samarium ​Lexadronum

Samarium ​Sm 153 le​xidronam

Sm-153-ED​TMP

Database ID(s)

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(Details...) Predicted Properties
LogP: ACD/LogP: -5.81
# of Rule of 5 Violations: 2
ACD/LogD (pH 5.5): -12.38 ACD/LogD (pH 7.4): -13.93
ACD/BCF (pH 5.5): 1 ACD/BCF (pH 7.4): 1
ACD/KOC (pH 5.5): 1 ACD/KOC (pH 7.4): 1
#H bond acceptors: 14 #H bond donors: 8
#Freely Rotating Bonds: 11 Polar Surface Area: 187.84 Å2
Index of Refraction: Molar Refractivity: cm3
Molar Volume: cm3 Polarizability: 10-24cm3
Surface Tension: dyne/cm Density: g/cm3
Flash Point: 485.2 °C Enthalpy of Vaporization: 138.57 kJ/mol
Boiling Point: 878.7 °C at 760 mmHg Vapour Pressure: 2.43E-34 mmHg at 25°C
(Details...) Feedback
DateSeverityStatusFeedback
5/29/2008 1:09:26 AMHighFixedPlease add Wikipedia text to this structure from http://en.wikipedia.org/wiki/Quadramet
Verdict: Fixed